insecticide resistance in insect vectors of disease with special reference to mosquitoes: a potential threat to global public health

نویسندگان

kaliyaperumal karunamoorthi department of environmental health sciences, unit of medical entomology and vector control, college of public health and medical sciences, jimma university , india +251-93547847, [email protected]; research and development centre, bharathiar university, coimbatore, india; department of environmental health sciences, unit of medical entomology and vector control, college of public health and medical sciences, jimma university , india +251-93547847, [email protected]

shanmugavelu sabesan vector control research centre (indian council of medical research), indira nagar, india

چکیده

context arthropod-borne diseases are remaining as a major public health issue in the resource-constrained settings. mosquitoes are closely associated with mankind since time immemorial and play an important role in the transmission of many dreadful diseases like malaria, filariasis, japanese encephalitis, dengue and yellow fever. over the decades, vector control is an important element to minimize the vector-borne disease burden worldwide and in fact, it heavily relies upon synthetic insecticides as a mainstay. however the overuse and misuse of insecticides have led to the emergence of resistance, which undermines the potentiality of vector control. evidence acquisition in order to pursue effective research pertained to this issue, a detailed search on scopus, medline, google scholar and academic premier databases has been conducted between the time periods of 1955 and 2012. results over the past six decades, insecticides are serving as one of the important arsenals in the fight against vector-borne diseases to save hundreds of millions of lives. consequently, in the last decade we have attained a remarkable success to combat with many diseases particularly malaria due to the combined effect of indoor residual spraying (irs) and long-lasting insecticidal nets (llins). currently, malaria mortality rates have drastically fallen by more than 25% globally, 33% in sub-saharan africa and over a million lives have been saved attributable to massive scale-up of llins and irs. since, both llins and irs are cost-effective and robust form of interventions; they are serving as a central pillar in the national malaria control programmes (nmcps) of malaria endemic countries. nevertheless, llins are easy-to-deliver, most economical and practical even in the resource-poor settings, where implementation of irs is not feasible. the heavy reliance, recurrent and inappropriate insecticide applications are key sources for resistance which is a potential threat to the global public health. therefore, it has to be addressed immediately to sustain the recent success of vector control, unless otherwise it would become uncertain. conclusions though, development of resistance is an evolutionary phenomenon, it can be tackled judiciously by implementing appropriate and comprehensive resistance monitoring and management strategies within the framework of integrated vector management. this scrutiny recommends the following measures; (i) identification of effective novel tools for monitoring and evaluation, (ii) searching for alternative interventions to minimize the further resistance evolution as well as to preserve the efficiency of existing insecticides, (iii) exploration of next generation vector control tools in terms of nets and new classes of non-pyrethroid insecticide formulation with new mode of action, (iv) building partnership by bringing together the people actively engaged in the vector control, like public health experts, policy-makers, researchers, medical entomologists and insecticide manufacturers, could ideally pave the way to collectively address the current debacle in the near future.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Free roaming dogs: a threat to public health

Free roaming dogs are increasing in numbers. They live in unhygienic conditions and are not vaccinated mostly. They create several problems in the community, particularly health threats to human. Dog biting is a commonly reported case in some hospitals in Bangladesh. Rabies is one of the killers of people in Bangladesh and transmission occurs mostly due the dog biting. Death commonly occurs in ...

متن کامل

‏‎a comparative study of language learning strategies employmed by bilinguals and monolinguals with reference to attitudes and motivation‎‏

هدف از این تحقیق بررسی برخی عوامل ادراکی واحساسی یعنی استفاده از شیوه های یادگیری زبان ، انگیزه ها ونگرش نسبت به زبان انگلیسی در رابطه با زمینه زبانی زبان آموزان می باشد. هدف بررسی این نکته بود که آیا اختلافی چشمگیر میان زبان آموزان دو زبانه و تک زبانه در میزان استفاده از شیوه های یادگیری زبان ، انگیزه ها نگرش و سطح مهارت زبانی وجود دارد. همچنین سعی شد تا بهترین و موثرترین عوامل پیش بینی کننده ...

15 صفحه اول

Implication of Micronutrients in Agriculture and Health with Special Reference to Iron and Zinc

The green revolution fulfilled the food demand of crowded millions. From the time of green revolution to till date high yielding and fertilizer responsive varieties have evolved to increase the production per unit area. To improve the productivity only major nutrients are concentrated almost in all crops. Though the importance of micronutrient realized during past decades in most of the crops b...

متن کامل

from linguistics to literature: a linguistic approach to the study of linguistic deviations in the turkish divan of shahriar

chapter i provides an overview of structural linguistics and touches upon the saussurean dichotomies with the final goal of exploring their relevance to the stylistic studies of literature. to provide evidence for the singificance of the study, chapter ii deals with the controversial issue of linguistics and literature, and presents opposing views which, at the same time, have been central to t...

15 صفحه اول

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
health scope

جلد ۲، شماره ۱، صفحات ۴-۱۸

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023